RNDr. Veronika Huntošová, PhD.

Current positions: 

• researcher – head of Confocal microscopy and Time resolved microscopy laboratories

Education:

• 2001 – 2004 Safarik University Kosice (Slovakia) – Bachelor of Science in Physics
• 2004 – 2006 Safarik University Kosice (Slovakia) – Master of Science in Biophysics
• 2008 Safarik University Kosice – rigorous exam RNDr. in Physic
• 2006 – 2010 Safarik University Kosice (Slovakia) and Pierre et Marie Curie University in Paris (France) – double diploma Philosophiae doctor in biophysics and Docteur de l’Universite Pierre et Marie Curie ED 387 Sorbonne Universites
• 2011 – 2013 Post-Doc fellow, Ecole Polytechnique Federale de Lausanne (Switzerland)

Research interests:

• Monitoring of cell/tissue oxygenation and oxidative stress by steady state and time-resolved microscopy;
• Monitoring of cell signalling related to cell survival, utophagy and apoptosis in cancer;
• Development of nanoscale transport systems for cancer targeting;
• Development of nanoparticles for bioimaging and diagnostic
• Application of avian chorioallantoic membrane model for photodiagnosis, photodynamic therapy, and tumor targeting;

 

• Actual project:

principal investigator:

• • Breast cancer organoid on a chip for fluorescence lifetime imaging of autophagy and apoptosis induced by targeted treatment with designed ankyrin repeat protein (BCOrgFluorIDA) funded by the EU NextGenerationEU through the Recovery and Resilience Plan for Slovakia under the project No. 09I03-03-V04-00007, 219 514. 80 € (2024-2026a)
  • Valorization of Light-Activated Medicinal Plant By-Products for Novel Biotechnologies and Edible Crop Production (VALOR-LIGHT), Coordinator University of Innsbruck (PI – S. Moser) AURORA initiative, 16 000. 00 €, (2024 - 2026) UPJŠ in Košiciach as associated partner AURORA
  • canSERV programme & EuroBioimaging Titile of the Project: HER2 targeted treatment of breast cancer with genetically coded photosensitizer (2024-2025)
  • Design of modular anticancer nanoparticles for morpho-molecular functional drug response investigation of cells and patient-derived organoids (MO3), bilateral APVV project between SLOVAKIA and AUSTRIA: SK-AT-23-0001, 8 000 € (2024-2026) PI – V. Huntošová (Z. Jurašeková replaced to be PI after achievement of BCOrgFluorIDA)

 

co-investigator:

 

Past projects:

principal investigator:

• • Euro-BioImaging & ISIDORe Titile of the Project: Interaction of metal organic framework transport system for antivirotics delivery with cells affected by SARS-CoV-2 (2023)
    
    
     
  • • Czech bioimaging Title of the Project: Imaging mitochondrial heterogeneity and lipid composition change in glioblastoma cells from 3D spheroids exposed to newly synthesized sphingolipids (2023)
    • VEGA1/0156/18 – Title of the Project: Time-resolved imaging of oxygen consumption in cancer cells during photo-dynamic therapy (2018-2020)
      
      
       
    • Sciex-NMSch N° 10.142 SVK – Title of the Project: Measurement of the tissue oxygenation based on the time-resolved detection of the delayed fluorescence of photosensitizers – scientific exchange program NMS-CH 18 months fellowship at EPFL in Lausanne, Switzerland (2011-2013)
      
      
       
    • VVGS PF 11/2009/F Title of the Project: Monitoring the level of intracellular hypericin aggregation by fluorescence recovery measurements – project for young scientist at UPJS (2009-2010)
      
      
      
       
    • Bourse de cotutelle de thèse BGF – Fellowship from French Government for double diploma PhD at UPJŠ in Košice and UPMC in Paris, France (2007-2010)

    •  co-investigator:

    • Pan-European Network in Lipidomics and EpiLipidomics (EpiLipidNET), COST action CA19105 (2020-2024) (PI - R. Domingues), V. Huntošová – participation in WG4 (Integration of (epi)lipidomics with Lipid signalling and mechanisms of action).
    • VEGA 1/0187/23 Title of the Project: Effect of photobiomodulation in 2D and 3D cell model of Parkinson disease (2023-2025)
    • APVV-21-0333 Title of the Project: Flexible microstructures and microrobots for biomedical ‘lab-onchip’ applications (2022-2026)
    • VVGS PCOV vvgs-2022-2408 Title of the Project: Development and study of functional Heusler nanowires for bio-application (2022-2023)
    • APVV-20-0340 Title of the Project: Development of efficient genetically encoded photosensitizers (2021-2024)
    • H2020-MSCA WIDESPREAD-05-2020: CasProt – Fostering high scientific quality in protein research in Eastern Slovakia, WIDESPREAD-05-2020: Twinning (2020-2023)
    • OPII-VA/DP/2020/9.4-01: BioPickmol – Development of nanosensor photonic systems for fast detection of viruses using directed protein evolution methods, ITMS2014+: 313011AUW6 (2021-2023)
    • OPVaI-VA/DP/2018/1.2.1-08: Open scientific community for modern interdisciplinary research in medicine (Acronym: OPENMED), ITMS2014+: 313011V455 supported by the Operational Programme Integrated Infrastructure (2019-2023)
    • COST Action CA17121 – Title: Correlated multimodal imaging in life sciences (COMULIS) (2018-2022) – management committee member for Slovakia
    • VEGA1/0421/18 – Title of the Project: Photobiostimulation as a mitochondrial dysfunction therapy (PHOBIOPIA) (2018-21)
    • APVV-15-0485 – Title of the Project: Towards highly selective cancer treatment: endogenous lipoprotein-DARPin complexes as a new generation of targeted drug delivery vehicles (2016-2020)
      
      
      
       
    • VEGA1/0156/18 – Title of the Project: Time-resolved imaging of oxygen consumption in cancer cells during photo-dynamic therapy (2018-2020)
    • VEGA 1/0425/15 – Molecular mechanisms of endothelial cell responses to oxidative stress at hypoxia (HYPOXENCELL) (2015-2017)
    • 7RP EÚ „Fostering Excellence in Multiscale Cell Imaging“ (CELIM) (2013-2016)
    • OPVaV – 2009/2.1/02-SORO: CEVA Centres of excellence for atherosclerosis research, ITMS 26220120040 (2010-2013)
    • APVV-LPP 0337-06 Photodynamic therapy of cancer in the light of new molecular knowledge (2006-2010)
    • APVV-0449-07 Targeted photodynamic therapy of cancer: from drug transport through cell signaling pathways up to in vivo model. (2008-2010)

    • Collaborations:

    • LIFMET – Dr. Wagnieres Group– EPFL, Lausanne, Switzerland
    • Department of Biophysics and Cell Biology –assoc. prof. Vamosi group -Debrecen University, Debrecen, Hungary
    • Center for medical physics and biomedical engineering- prof. Unterhuber-Medical University of Vienna, Austria
    • LABORATOIRE JEAN PERRIN– Dr, Sureau group– UPMC, Paris, France
    • AS CR – Institute of Macromolecular Chemistry, Polymer Particles, Czech Academy of Sciences, Dr. Horak group – Prague, Czech Republic
    • SAS – Institute of Animal Biochemistry and Genetics CBS, Dr. Macajova and Dr. Bilcik group – Bratislava, Slovakia
    • SAS – Institute of Experimental Physics – Siposovaand  Musatov group – Kosice, Slovakia
    • SAS – Polymer Institute, Department for biomaterials research, Dr. Kronek group – Bratislava, Slovakia

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